[The range of individual sensitivity to adhesion by Neisseria meningitidis serogroup B in young men]

Zh Mikrobiol Epidemiol Immunobiol. 1995 Jul-Aug:(4):17-9.
[Article in Russian]

Abstract

5,340 young adult males, including 5,149 healthy persons, 141 N. meningitidis carriers, 25 patients with generalized meningococcal infection and 6 patients with nasopharyngitis of meningococcal etiology, were examined. The study revealed that red blood cells of 17.4% of healthy persons were highly sensitive to N.meningitidis adhesion (adhesion indices equal to 0.25 and less), red blood cells of 20.4% of persons had low sensitivity to N.meningitidis adhesion (adhesion indices equal to 2 and greater). All other persons with high sensitivity of their red blood cells proved to be patients with meningococcal infection or carriers of N.meningitidis of the same group.

Publication types

  • Comparative Study

MeSH terms

  • Adhesins, Bacterial / pharmacology
  • Adolescent
  • Adult
  • Bacterial Adhesion*
  • Carrier State / microbiology
  • Erythrocytes / drug effects
  • Humans
  • Male
  • Meningitis, Meningococcal / microbiology
  • Meningococcal Infections / microbiology
  • Nasopharyngitis / microbiology
  • Neisseria meningitidis / classification
  • Neisseria meningitidis / pathogenicity*
  • Serotyping

Substances

  • Adhesins, Bacterial