Abstract
A case is presented of a patient who developed a gastrosplenic fistula during a course of chemotherapy for differentiated histiocytic lymphoma. The fistula was observed during upper gastrointestinal endoscopy (gastroscopy) and confirmed by CT scan with contrast. The fistula was followed endoscopically and noted to have closed spontaneously with confirmed closure at laparotomy. The clinical management of this complication is discussed, and the literature pertaining to this rare condition is reviewed.
MeSH terms
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use
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Cyclophosphamide / administration & dosage
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Doxorubicin / administration & dosage
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Fistula / diagnosis
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Fistula / etiology*
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Gastric Fistula / diagnosis
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Gastric Fistula / etiology*
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Humans
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Lymphoma, Large B-Cell, Diffuse / complications*
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Lymphoma, Large B-Cell, Diffuse / drug therapy
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Lymphoma, Large B-Cell, Diffuse / pathology
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Male
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Middle Aged
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Prednisone / administration & dosage
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Splenic Diseases / diagnosis
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Splenic Diseases / etiology*
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Vincristine / administration & dosage
Substances
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Vincristine
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Doxorubicin
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Cyclophosphamide
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Prednisone