Chromosomal translocation, t(1;11)(q12;p15), in an extragonadal immature teratoma

Cancer Genet Cytogenet. 1997 Aug;97(1):79-80. doi: 10.1016/s0165-4608(97)00196-9.

Abstract

A case of immature teratoma arising from the base of the skull is reported. The cytogenetic analysis revealed t(1;11)(q12;p15) as a sole chromosomal abnormality, suggesting that the breakpoint on chromosome 11 plays an important role in the early oncogenesis of human germ cell tumors (GCTs).

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chromosomes, Human, Pair 1 / genetics
  • Chromosomes, Human, Pair 11 / genetics
  • Humans
  • Male
  • Middle Aged
  • Nasal Cavity*
  • Nose Neoplasms / genetics*
  • Teratoma / genetics*
  • Translocation, Genetic*