Identification of Doppler microembolic signals with a bigate probe in patients with prosthetic heart valves

Eur J Med Res. 1997 Jul 28;2(7):299-301.

Abstract

Background and purpose: The applicability of a bigate probe, simultaneously harvesting two spatially separated vessel segments, in the identification of Doppler microembolic signals (MES) was evaluated.

Methods: One hundred and ninety-seven patients with artificial heart valves were bilaterally monitored over two segments of each middle cerebral artery, with a minimal distance of 5 mm between them, using 2 MHz probes. Time delay in the appearance of high intensity transients between the two segments was calculated off-line, using dedicated software, integrated in the Doppler device.

Results: Bigate monitoring was feasible in 96% of patients. MES prevalence and counts were 37% and 26 (18-44) respectively. All but 8.8% of the 2932 MES signals recorded appeared in both Doppler channels, with a time delay of 4.4 (4.2-4.7) msec (range between 0 and 34 msec). Time delay in 97% of artifact signals was under 1 msec. Application of 1 msec as low and 20 msec as high cut-off point between MES and artifacts resulted in the correct identification of 97% of artifacts and 89.6% of MES.

Conclusions: The multigate approach is a reliable method for identification of Doppler microembolic signals in patients with prosthetic heart valves. The value of this technique in other patient groups remains to be evaluated.

MeSH terms

  • Aortic Valve
  • Cerebral Arteries / diagnostic imaging*
  • Cerebral Arteries / pathology
  • Female
  • Heart Valve Prosthesis*
  • Humans
  • Intracranial Embolism and Thrombosis / diagnostic imaging*
  • Intracranial Embolism and Thrombosis / epidemiology*
  • Male
  • Middle Aged
  • Mitral Valve
  • Prevalence
  • Ultrasonography, Doppler, Transcranial