Movement disorders associated with withdrawal from high-dose intravenous haloperidol therapy in delirious ICU patients

Chest. 1997 Jun;111(6):1778-81. doi: 10.1378/chest.111.6.1778.

Abstract

Intravenous haloperidol is recommended as the drug of choice to treat delirium in ICU patients. Movement disorders and other adverse events commonly occur with oral haloperidol use but are rarely seen with IV haloperidol use, and withdrawal symptoms have not been reported with short-term ICU use. We describe self-limited dyskinesia during withdrawal of high-dose continuous IV haloperidol therapy in five ICU patients.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Critical Care*
  • Delirium / complications*
  • Delirium / drug therapy
  • Dyskinesia, Drug-Induced / diagnosis
  • Dyskinesia, Drug-Induced / etiology*
  • Female
  • Haloperidol / administration & dosage
  • Haloperidol / adverse effects*
  • Humans
  • Infusions, Intravenous
  • Male
  • Middle Aged
  • Substance Withdrawal Syndrome / diagnosis*
  • Time Factors

Substances

  • Haloperidol