The epidemic situation associated with tuberculosis has tended recently to aggravate in Uzbekistan, in the Aral region, arid and rural areas in particular. The pattern of detected tuberculosis has become worse. The reasons for epidemiological troubles and deteriorated organized antituberculosis work in the republic are clarified in the paper. A governmental programme for tuberculous prevention and morbidity reduction with antituberculous measures being financed has been prepared, which determines immediate tuberculosis control strategy. Stepwise implementation of this programme will prevent the further spread of this infection and enhance the efficiency of tuberculosis treatment.