1579 stool samples from patients with travel-associated diarrhea were examined by conventional culture methods to detect Shigella spp. (48 positive samples or 3.2%) and by PCR to detect shigellae and enteroinvasive Escherichia coli (EIEC) (87 positive samplers or 5.8%). The numerical relation of shigellae to EIEC in PCR-positive samples was about 60 to 40%. However, the lack of discrimination between shigellae and EIEC is not important for the physician because the choice of antibiotics remains the same.