Abstract
I.v. administration of trypsinogen potentiated the pentagastrin-induced secretion of gastric glands and reduced the leu-enkephalin effect upon them in the fistula dogs. Intraperitoneal administration of trypsinogen enhanced the pepsinogen synthesis by the gastric glands, did not change the hydrolases activity in pancreas homogenate in rats.
MeSH terms
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Animals
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Dogs
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Enkephalin, Leucine / pharmacology
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Gastric Juice / chemistry
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Gastric Juice / drug effects
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Gastric Juice / metabolism
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Gastric Mucosa / drug effects*
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Gastric Mucosa / metabolism
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Pancreas / drug effects*
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Pancreas / metabolism
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Pentagastrin / pharmacology
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Rats
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Receptors, Peptide / drug effects*
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Receptors, Peptide / physiology
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Stimulation, Chemical
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Trypsinogen / pharmacology*
Substances
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Receptors, Peptide
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Enkephalin, Leucine
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Trypsinogen
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Pentagastrin