Intramyelinic edema in chronic inflammatory demyelinating polyneuropathy

Clin Neuropathol. 1996 Jan-Feb;15(1):17-21.

Abstract

We describe a patient affected by chronic inflammatory demyelinating polyneuropathy (CIDP) whose sural nerve biopsy revealed a marked edema of the myelin sheath. Since this change has been previously described in human peripheral nerves only in CIDP patients, we suggest that intramyelinic edema may have a role in the pathogenesis of demyelinating neuropathies.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biopsy
  • Chronic Disease
  • Demyelinating Diseases / complications
  • Demyelinating Diseases / drug therapy
  • Demyelinating Diseases / pathology*
  • Edema / complications
  • Edema / drug therapy
  • Edema / pathology*
  • Humans
  • Male
  • Middle Aged
  • Myelin Sheath / pathology*
  • Neuritis / complications
  • Neuritis / drug therapy
  • Neuritis / pathology*
  • Peripheral Nervous System Diseases / complications
  • Peripheral Nervous System Diseases / drug therapy
  • Peripheral Nervous System Diseases / pathology*
  • Sural Nerve / pathology*

Grants and funding