Antibiotic phenol nor-triterpenes from Maytenus canariensis

A G González; N L Alvarenga; A G Ravelo; I A Jiménez; I L Bazzocchi; N J Canela; L M Moujir

doi:10.1016/0031-9422(96)00205-1

Antibiotic phenol nor-triterpenes from Maytenus canariensis

Phytochemistry. 1996 Sep;43(1):129-32. doi: 10.1016/0031-9422(96)00205-1.

Authors

A G González¹, N L Alvarenga, A G Ravelo, I A Jiménez, I L Bazzocchi, N J Canela, L M Moujir

Affiliation

¹ Instituto Universitario de Bio-Orgánica Antonio González, Universidad de La Laguna, Tenerife, Canary Islands, Spain.

PMID: 8987507
DOI: 10.1016/0031-9422(96)00205-1

Abstract

The new phenols 6-oxo-tingenol, 3-O-methyl-6-oxo-tingenol and 6-oxo-iguesterol were isolated from the root bark of Maytenus canariensis. Their structures were determined by 1H and 13C NMR spectroscopic studies, including HMQC, HMBC, DEPT and ROESY and chemical transformations. The synthesis of 6-oxo-tingenol was achieved from tingenone. These compounds exhibit antibiotic activity against Gram-positive bacteria.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anti-Bacterial Agents / chemistry
Anti-Bacterial Agents / isolation & purification*
Carbon Isotopes
Magnetic Resonance Spectroscopy
Mass Spectrometry
Plant Roots / chemistry*
Plants, Medicinal / chemistry*
Protons
Terpenes / chemistry
Terpenes / isolation & purification*

Substances

Anti-Bacterial Agents
Carbon Isotopes
Protons
Terpenes