Reactivation of caprine herpesvirus 1 in latently infected goats

Comp Immunol Microbiol Infect Dis. 1996 Sep;19(4):275-81. doi: 10.1016/0147-9571(96)00014-8.

Abstract

The authors report CapHV.1 reactivation in two latently infected adult goats treated with dexamethasone (DMS) (4.40 mg/kg BW) for 6 days. Virus was reisolated from vaginal swabs from the 3rd to the 12th day post-treatment with DMS and from nasal swabs for 2 days (6th and 7th day post-treatment). The animals also showed an increase of neutralizing antibody (SN) titer to CapHV.1 3 weeks after the end of treatment with DMS.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cell Line
  • Dexamethasone / therapeutic use
  • Goat Diseases / virology*
  • Goats
  • Herpes Simplex / veterinary*
  • Herpes Simplex / virology
  • Neutralization Tests
  • Polymorphism, Restriction Fragment Length
  • Simplexvirus / growth & development*
  • Simplexvirus / isolation & purification
  • Viral Plaque Assay
  • Virus Activation*
  • Virus Latency

Substances

  • Dexamethasone