The development of a treatment protocol for patients with chronic radiation-induced rectal bleeding

Aust N Z J Surg. 1996 Oct;66(10):680-5. doi: 10.1111/j.1445-2197.1996.tb00717.x.

Abstract

BACKGROUNDS AND METHODS: This study reviews the clinical features and reports the preliminary results of treatment of 34 consecutive patients with clinically significant bleeding from chronic, radiation-induced proctitis, using a combination of endoscopic YAG Laser and the application of topical formalin dressings to the rectal mucosa.

Results: Bleeding ceased in 25 patients (74%); bleeding continued but occurred only slightly and occasionally in five patients (15%); and three patients required operation to control the bleeding (9%). One patient relapsed after treatment and died while receiving a further transfusion.

Conclusions: This experience has been used to develop a management protocol for patients with this serious complication.

MeSH terms

  • Administration, Topical
  • Aged
  • Chi-Square Distribution
  • Chronic Disease
  • Clinical Protocols
  • Colonoscopy / methods
  • Confidence Intervals
  • Female
  • Follow-Up Studies
  • Formaldehyde / administration & dosage
  • Gastrointestinal Hemorrhage / surgery*
  • Hemoglobins / analysis
  • Humans
  • Laser Coagulation / adverse effects
  • Male
  • Middle Aged
  • Proctitis / surgery*
  • Radiation Injuries / surgery*
  • Telangiectasis / surgery
  • Treatment Outcome
  • Urogenital Neoplasms / radiotherapy

Substances

  • Hemoglobins
  • Formaldehyde