Confirmation of early menopause in fragile X carriers

Am J Med Genet. 1996 Aug 9;64(2):370-2. doi: 10.1002/(SICI)1096-8628(19960809)64:2<370::AID-AJMG27>3.0.CO;2-B.

Abstract

Fragile X carriers have a median age of menopause 6 to 8 years earlier than women in the general population, with 28% experiencing premature ovarian failure defined as menopause before the age of 40 years. This information was obtained from 203 returned questionnaires from women in the UK Fragile X Society.

MeSH terms

  • Adult
  • Age Factors
  • Family
  • Female
  • Fragile X Syndrome / genetics*
  • Fragile X Syndrome / physiopathology*
  • Heterozygote*
  • Humans
  • Menopause*
  • Middle Aged
  • Primary Ovarian Insufficiency / epidemiology
  • Reference Values
  • Surveys and Questionnaires