A graphical approach for presenting linkage results from a genomic screen

Genet Epidemiol. 1995;12(6):807-12. doi: 10.1002/gepi.1370120646.

Abstract

Initially, a sib-pair linkage analysis was performed between the marker loci and six untransformed variables. Results from several variations of this initial analysis were compared using a graphical approach (P-plots) to simplify presentation. When results were compared to the generating model, most of the aspects of the generating model were recovered, although we did not find evidence of the polygenic component shared by Q2 and Q3, or evidence of linkage between MG4 and Q4 at the 0.01 level.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Chromosome Mapping
  • Computer Graphics*
  • Genetic Linkage*
  • Genetic Markers*
  • Genetic Testing / methods*
  • Genome, Human*
  • Humans
  • Nuclear Family

Substances

  • Genetic Markers