[Dyslipemia in type-2 diabetes. A risk factor for macroangiopathy?]

Aten Primaria. 1996 Jun 15;18(1):3-8.
[Article in Spanish]

Abstract

Objective: To study the association of dyslipemia with macroangiopathy in patients with type II diabetes mellitus.

Design: Descriptive crossover study.

Setting: An urban health district with a socially and economically depressed elderly population.

Patients: A randomised sample among the diabetics registered in the health district (n = 449).

Measurements and main results: Different factors in the lipidic profile were studied, as was the presence of diabetic macroangiopathy and some of the associated risk factors. The following were considered cut-off figures with a predictive value of cardiovascular risk: overall cholesterol >or= 240 mg/dl (40% of the sample), HDL < 35 mg/dl (27%), LDL >or= 160 mg/dl (43%), triglycerides >or= 200 mg/dl (25%), atherogenic index >or= 4.5 (73%) and HDL/LDL balance >or= 0.2 (83%). 85.5% of the diabetics in the sample presented one of the lipidic disorders mentioned above. In the multivariant analysis only hypertriglyceridaemia was associated with a higher prevalence of peripheral vasculopathy.

Conclusions: A high percentage of patients with type II DM presented disorders in their lipidic profile. But, unlike the norm in the general population, only hypertriglyceridaemia displayed a statistically significant association with diabetic macroangiopathy. The role of the other dyslipemic factors was limited.

Publication types

  • English Abstract

MeSH terms

  • Aged
  • Cross-Sectional Studies
  • Diabetes Mellitus, Type 2 / blood
  • Diabetes Mellitus, Type 2 / complications*
  • Diabetes Mellitus, Type 2 / epidemiology
  • Diabetic Angiopathies / blood
  • Diabetic Angiopathies / epidemiology
  • Diabetic Angiopathies / etiology*
  • Female
  • Humans
  • Hyperlipidemias / blood
  • Hyperlipidemias / complications*
  • Hyperlipidemias / epidemiology
  • Lipids / blood
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Random Allocation
  • Risk Factors
  • Socioeconomic Factors
  • Spain / epidemiology
  • Urban Population / statistics & numerical data

Substances

  • Lipids