Analysis of CA repeat polymorphisms places three human gene loci on the 8p linkage map

R Bruskiewich; T Everson; L Ma; L Chan; M Schertzer; J P Giacobino; P Muzzin; S Wood

doi:10.1159/000134369

Analysis of CA repeat polymorphisms places three human gene loci on the 8p linkage map

Cytogenet Cell Genet. 1996;73(4):331-3. doi: 10.1159/000134369.

Authors

R Bruskiewich¹, T Everson, L Ma, L Chan, M Schertzer, J P Giacobino, P Muzzin, S Wood

Affiliation

¹ Department of Medical Genetics, University of British Columbia, Vancouver, Canada.

PMID: 8751389
DOI: 10.1159/000134369

Abstract

The gene loci for luteinizing hormone-releasing hormone (LHRH), the beta-3 adrenergic receptor (ADRB3), and heregulin (HGL) have been assigned to the short arm of human chromosome 8, but the positions of these loci on the human genetic linkage map have not been previously reported. We have isolated simple tandem repeat polymorphisms (STRPs) for these loci. These STRPs enabled us to determine the genetic map locations for these genes.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Base Sequence
Chromosome Mapping
Chromosomes, Human, Pair 8 / genetics*
Dinucleotide Repeats*
Genes*
Genetic Linkage
Glycoproteins / genetics*
Gonadotropin-Releasing Hormone / genetics*
Humans
Molecular Sequence Data
Neuregulins
Receptors, Adrenergic, beta / genetics*
Receptors, Adrenergic, beta-3

Substances

Glycoproteins
Neuregulins
Receptors, Adrenergic, beta
Receptors, Adrenergic, beta-3
Gonadotropin-Releasing Hormone