1,103 fish-fillets belonging to 4 species were examined during one year, during a survey conducted among commercial marine fish-fillets in the Nantes area (west coast) in France. Anisakis simplex L3 were found in 3 different species and most of them are frequently present in coal fish (Pollachius virens) and whiting (Merlangius merlangus). We report 6 cases of human anisakiasis (3 certain cases and 3 probably cases). Diagnosis was established in 3 cases by microscopic analysis of intestin bowel specimens (eosinophilic granulomas and/or parasitic fragments) and in 3 cases gastroscopy. Serodiagnosis was positive in 1 case and the consumption of undercooked fishes was found in 5 cases. This work emphasizes the role of anisakiasis as a source of digestive symptoms and intestinal eosinophilic granuloma.