Abstract
The hormone abscisic acid (ABA) modulates a variety of developmental processes and responses to environmental stress in higher plants. A collection of mutations, designated era, in Arabidopsis thaliana that confer an enhanced response to exogenous ABA includes mutations in the Era1 gene, which encodes the beta subunit of a protein farnesyl transferase. In yeast and mammalian systems, farnesyl transferases modify several signal transduction proteins for membrane localization. The era1 mutants suggest that a negative regulator of ABA sensitivity must be acted on by a farnesyl transferase to function.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Abscisic Acid / pharmacology*
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Alkyl and Aryl Transferases*
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Amino Acid Sequence
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Arabidopsis / drug effects
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Arabidopsis / enzymology*
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Arabidopsis / genetics
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Arabidopsis / physiology
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Genes, Plant
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Germination
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Molecular Sequence Data
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Mutation
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RNA, Messenger / genetics
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RNA, Messenger / metabolism
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RNA, Plant / genetics
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RNA, Plant / metabolism
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Seeds / drug effects
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Seeds / enzymology
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Seeds / physiology
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Sequence Alignment
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Signal Transduction*
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Transferases / chemistry
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Transferases / genetics
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Transferases / metabolism*
Substances
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RNA, Messenger
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RNA, Plant
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Abscisic Acid
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Transferases
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Alkyl and Aryl Transferases
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p21(ras) farnesyl-protein transferase
Associated data
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GENBANK/U44849
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GENBANK/U46574