X-ray structure investigations of potential beta-blockers. II.6,7-Dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline

T A Olszak; A Stepień; M J Grabowski; E Brzezińska

doi:10.1107/s0108270195013606

X-ray structure investigations of potential beta-blockers. II.6,7-Dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline

Acta Crystallogr C. 1996 Apr 15:52 ( Pt 4):1038-40. doi: 10.1107/s0108270195013606.

Authors

T A Olszak¹, A Stepień, M J Grabowski, E Brzezińska

Affiliation

¹ Department of Crystallography, University of Ldź, Poland.

PMID: 8624238
DOI: 10.1107/s0108270195013606

Abstract

The saturated part of the isoquinoline moiety in the title compound, C17H19NO2, has a twist conformation and the phenyl ring substituent is in an equatorial position. The absolute configuration of the molecule is R and molecules form infinite chains by means of weak hydrogen bonds.

MeSH terms

Adrenergic beta-Antagonists / chemistry*
Crystallography, X-Ray
Hydrogen Bonding
Isoquinolines / chemistry*
Molecular Conformation
Molecular Structure
Tetrahydroisoquinolines*

Substances

Adrenergic beta-Antagonists
Isoquinolines
Tetrahydroisoquinolines
1-phenyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline