Abstract
Three new tetrasaccharide glycosides, differing from one reported previously in the type of short-chain fatty acids ester-linked to the tetrasaccharide core, have been isolated and identified from an oligosaccharide fraction of Ipomea stans. Preliminary screening tests showed that the fraction containing these compounds had pronounced cytotoxicity towards three human tumor cell lines as well as specific antibiotic activity against two bacterial strains.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / chemistry
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Anti-Bacterial Agents / isolation & purification*
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Anti-Bacterial Agents / pharmacology
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Antineoplastic Agents, Phytogenic / chemistry
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Antineoplastic Agents, Phytogenic / isolation & purification*
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Antineoplastic Agents, Phytogenic / pharmacology
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Bacteria / drug effects
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Carbohydrate Sequence
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Chromatography, High Pressure Liquid
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Drug Screening Assays, Antitumor
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Glycosides / chemistry
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Glycosides / isolation & purification*
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Glycosides / pharmacology
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Humans
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Magnetic Resonance Spectroscopy
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Microbial Sensitivity Tests
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Molecular Sequence Data
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Oligosaccharides / chemistry
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Oligosaccharides / isolation & purification*
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Oligosaccharides / pharmacology
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Plants, Medicinal / chemistry*
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Tumor Cells, Cultured
Substances
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Anti-Bacterial Agents
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Antineoplastic Agents, Phytogenic
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Glycosides
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Oligosaccharides