Abstract
The structures of two alpha-(1-->3)-alpha-D-xylo-mannans were determined. The different antiviral activity of the xylo-mannans from Nothogenia fastigiata was explained on the basis of a flexible backbone, molecular size, content and distribution of sulfate groups and of the single stubs of beta-(1-->2)-linked D-xylose.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antiviral Agents / chemistry*
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Antiviral Agents / isolation & purification
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Antiviral Agents / pharmacology
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Carbohydrate Conformation
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Herpesvirus 1, Human / drug effects
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Magnetic Resonance Spectroscopy
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Mannans / chemistry*
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Mannans / isolation & purification
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Mannans / pharmacology
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Methylation
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Molecular Weight
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Monosaccharides / analysis
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Optical Rotation
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Seaweed / chemistry*
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Spectroscopy, Fourier Transform Infrared
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Sulfuric Acid Esters / chemistry*
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Sulfuric Acid Esters / isolation & purification
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Sulfuric Acid Esters / pharmacology
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Xylose / chemistry
Substances
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Antiviral Agents
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Mannans
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Monosaccharides
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Sulfuric Acid Esters
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Xylose