A new perspective on muscle contraction

FEBS Lett. 1993 Jun 28;325(1-2):59-62. doi: 10.1016/0014-5793(93)81413-t.

Abstract

Recent experimental findings suggest that the myosin cross-bridge theory may no longer be adequate to account for certain basic facts concerning muscle contraction. A newly-proposed mechanism based on length changes in actin filaments might be the basis for a simpler explanation for how the free energy of ATP hydrolysis can be transduced into work by muscle fibers.

Publication types

  • Review

MeSH terms

  • Actins / physiology
  • Adenosine Triphosphatases / metabolism
  • Models, Biological*
  • Muscle Contraction / physiology*
  • Muscles / physiology

Substances

  • Actins
  • Adenosine Triphosphatases