Abstract
We describe a 65-year-old woman born and living in Northern Italy affected by non tropical spastic tetraparesis and her asymptomatic husband presenting HTLV-1 sequences in their lymphocytes detected by polymerase chain reaction (PCR). We discuss the significance of the case and the mechanism involved in HTLV-1 infection and the relationship with neurological disorders, stressing that this case is the first reported in Italy.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Blotting, Southern
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Blotting, Western
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Cells, Cultured
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DNA Probes
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DNA, Viral / blood
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DNA, Viral / isolation & purification
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Enzyme-Linked Immunosorbent Assay
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Female
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Genes, env
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Genes, pX
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Genes, pol
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HTLV-I Antibodies / blood
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HTLV-I Antigens / blood
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HTLV-I Infections / diagnosis
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HTLV-I Infections / microbiology*
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Human T-lymphotropic virus 1 / genetics
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Human T-lymphotropic virus 1 / immunology
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Human T-lymphotropic virus 1 / isolation & purification*
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Humans
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Lymphocytes / microbiology*
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Male
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Middle Aged
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Paralysis / diagnosis
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Paralysis / microbiology*
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Polymerase Chain Reaction
Substances
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DNA Probes
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DNA, Viral
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HTLV-I Antibodies
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HTLV-I Antigens