Two members of the S-lac lectin gene family, LGALS1 and LGALS2, reside in close proximity on human chromosome 22q12-q13

Genomics. 1993 Feb;15(2):418-20. doi: 10.1006/geno.1993.1078.

Abstract

S-lac lectins are a family of soluble lactose-binding proteins thought to function in the control of cell growth. We now report the chromosomal mapping of two members of the family, termed L-14-I and L-14-II, to the q12-q13 region of human chromosome 22, suggesting the possibility of a cluster of genes for lactose-binding proteins.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Carrier Proteins / genetics*
  • Chromosome Mapping
  • Chromosomes, Human, Pair 22*
  • Escherichia coli Proteins*
  • Humans
  • Hybrid Cells
  • In Situ Hybridization
  • Lactose / metabolism*
  • Lectins / genetics*
  • Mice
  • Monosaccharide Transport Proteins*
  • Multigene Family*
  • Symporters*

Substances

  • Carrier Proteins
  • Escherichia coli Proteins
  • LacY protein, E coli
  • Lectins
  • Monosaccharide Transport Proteins
  • Symporters
  • Lactose