A typical affection of the pigment epithelium was described for the first time by Scuderi and colleagues in 1948, characterized by visual loss and the ophthalmoscopic finding of exudative, yellowish white spots at the posterior pole, a favorable course and a quick healing, defined as "benign external exudative retinitis." We illustrate another 13 cases of this disease angiographically studied and define its characteristics, proposing the denomination of "acute posterior multifocal placoid pigment epitheliopathy." We underline that the multiple placoid pigment epitheliopathy described by Gass and co-workers in 1968 is identical to the disease described by Scuderi in 1948.