Malignant mixed mullerian tumors of the fallopian tube

Gynecol Oncol. 1993 Aug;50(2):239-43. doi: 10.1006/gyno.1993.1199.

Abstract

Malignant mixed mullerian tumors of the female genital tract are rare and occur least commonly in the fallopian tube. A case is reported and 51 other cases in the literature are reviewed. The mean age at diagnosis is 59 years. Abdominal pain is the most common presenting complaint. A pelvic or abdominal mass is present in 75% of patients. The diagnosis is not usually established until surgery, with the most common preoperative diagnosis being ovarian malignancy. Seventy-five percent of cases had tumor extension beyond the fallopian tube at the time of surgery. Treatment has focused on surgery with postoperative radiation and/or chemotherapy. Prognosis is poor, with fewer than half of patients surviving 2 years. Recent reports suggest improved outcome with platinum-based chemotherapy but data are limited.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Carboplatin / therapeutic use
  • Chemotherapy, Adjuvant
  • Fallopian Tube Neoplasms / diagnosis*
  • Fallopian Tube Neoplasms / drug therapy
  • Fallopian Tube Neoplasms / surgery
  • Female
  • Humans
  • Neoplasm Recurrence, Local
  • Neoplasms, Germ Cell and Embryonal / diagnosis*
  • Neoplasms, Germ Cell and Embryonal / drug therapy
  • Neoplasms, Germ Cell and Embryonal / surgery
  • Prognosis

Substances

  • Carboplatin