Surveillance in patients with stage I testicular nonseminomatous germ cell tumors

Cancer Invest. 1993;11(1):10-4. doi: 10.3109/07357909309020255.

Abstract

Fourteen patients with testicular nonseminomatous germ cell tumor, clinical stage I were entered into a surveillance study. Median age was 31 (range 18-58). Three patients had pure tumor, and 11, mixed tumor. In 2 patients, vascular invasion was noted, and in 1, involvement of the spermatic cord. Serum alpha fetoprotein and beta subunit choriogonadotropin were high in 9 and in 3 patients, respectively. In median follow-up of 21 months (range 2-63), 3 patients relapsed: 1 had inguinal lymphadenopathy and 2 had lung metastases at 12, 4, and 16 months, respectively. Salvage chemotherapy PEB and PVB achieved complete response in the latter 2 patients for 6 and 49 months. Except for 1 patient lost to follow-up, all are alive.

MeSH terms

  • Adolescent
  • Adult
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local / diagnosis
  • Neoplasm Staging
  • Neoplasms, Germ Cell and Embryonal / pathology
  • Neoplasms, Germ Cell and Embryonal / surgery
  • Neoplasms, Germ Cell and Embryonal / therapy*
  • Orchiectomy
  • Prospective Studies
  • Testicular Neoplasms / pathology
  • Testicular Neoplasms / surgery
  • Testicular Neoplasms / therapy*