The Poison Information Centre answered in 1990 and 1991 in the mean 6000 inquiries year. Inquiries concerning mushrooms belong to the most severe ones, their number may be substantially different. In 1990 there were 38 inquiries regarding mushrooms, only 8 inquiries concerning Amanita phalloides, but in 1991 146 inquiries including 65 demanding symptoms and treatment of Amanita phalloides intoxication. In the same year 27 Amanita phalloides intoxications were confirmed on the basis of discharging reports from the hospitals, in seven cases fatal. As important prognostic factors seem the early visit of a physician and the treatment without delay. The influence of negative prognostic factors by Floersheim--short latency period, massive founding of spores and the lowering of the Quick test under 10% were not confirmed by the data of the Poison Information Centre.