The relationship between the location and the discharge of breast cancers in 50 cases was analyzed from May 1980 to May 1989. Those lesions were located beneath the areolae or near the areolae. Ductograms and cytology were very useful in the diagnosis. Most of them (72.7% and 69.2% respectively) belonged stage I. Five-year survival was 100% and 92.6% respectively. But those located far away from areola tended to become bigger and bigger, and invaded the large ducts. So the nipple discharge appeared. Most of them (69.2%) were in stage III. Five-year survival was 52.8%. The prognosis of this group was poorer than that of the former group.