Headache is one of man's most common afflictions. Increasing interest from the general population has contributed to the recent surge in research. This research relates to etiology or pathophysiology, treatment and impact of society. Headache can be a minor symptom or a symptom of serious underlying disease. As nurses, either in a health care facility or in our communities, we have a responsibility to keep abreast of current theories and treatments. Both presenters are currently involved in clinical trials of new headache medications for both children and adults. Behavioural Objectives: 1. Understand when a headache is a serious symptom and warrants further investigation. 2. Identify the different types of headache. 3. Describe the etiology of headache and its physical and psychological manifestations in child and adults with a particular emphasis on migraine. 4. Gain appreciation for the role of the clinical trials nurse.