[Pathophysiological basis of 3 subtypes in ganfeng neidong syndrome]

Zhongguo Zhong Xi Yi Jie He Za Zhi. 1993 Jul;13(7):391-6, 387.
[Article in Chinese]

Abstract

The multiple parameters of 3 Subtypes: Ganyang Huafeng Syndrome (GYHFS), Xuexu Shengfeng Syndrome and Yinxu Fengdong Syndrome of Ganfeng Neidong Syndrome were determined for the 1st time. It was found that there were several characteristics in GYHFS. (1) Disturbance of the cerebral blood flow and the damage of brain tissue was manifested by the abnormality of the bulbar conjunctival microcirculation, carotid Doppler ultrasonic determination and brainstem auditory and visual pathway, high blood viscosity, dysmnesia, free radical and lipid peroxidation injury and the changes of Zn, Cu, K and Mg after brain damage. (2) Stress status were expressed by the high plasma levels of cortisol, norepinephrine and epinephrine, decreased serum triiodothyronine level and hyperfunction of sympathetic nerve. (3) The marked changes of the regulating substance of the vessel smooth muscle function including the increased plasma levels of TXB2, TXB2/6-k-PGF1 alpha, and calmodulin, as well as decreased SP, ANP, CGRP. Other 2 subtypes had about the same changes of these parameters, but of milder disorders.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • 6-Ketoprostaglandin F1 alpha / blood
  • Adult
  • Aged
  • Blood Viscosity
  • Cerebral Hemorrhage / blood
  • Cerebral Hemorrhage / physiopathology*
  • Cerebral Infarction / blood
  • Cerebral Infarction / physiopathology*
  • Conjunctiva / blood supply
  • Diagnosis, Differential*
  • Female
  • Humans
  • Liver Diseases / blood
  • Liver Diseases / classification
  • Liver Diseases / physiopathology*
  • Male
  • Medicine, Chinese Traditional*
  • Microcirculation
  • Middle Aged
  • Thromboxane B2 / blood
  • Trace Elements / blood

Substances

  • Trace Elements
  • Thromboxane B2
  • 6-Ketoprostaglandin F1 alpha