Humoral immune response in human pulmonary tuberculosis: antibodies against Mycobacterium tuberculosis polysaccharide, protein and glycolipid antigens

Roum Arch Microbiol Immunol. 1993 Apr-Jun;52(2):109-19.

Abstract

Sera from 67 tuberculosis patients and 30 healthy subjects have been analyzed for the presence of specific antibodies against polysaccharide, protein and glycolipid antigens from H37Rv strain of Mycobacterium tuberculosis. The results proved the advantages of using the glycolipid antigens in diagnosing tuberculosis as well as the relationship between the antibodies level and the extension of the pulmonary tuberculous lesions.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Antibodies, Bacterial / blood*
  • Antibody Formation
  • Antigens, Bacterial / immunology*
  • Bacterial Proteins / immunology*
  • Enzyme-Linked Immunosorbent Assay / methods
  • Female
  • Glycolipids / immunology*
  • Humans
  • Male
  • Middle Aged
  • Mycobacterium tuberculosis / immunology*
  • Polysaccharides, Bacterial / immunology*
  • Sensitivity and Specificity
  • Tuberculosis, Pulmonary / diagnosis*
  • Tuberculosis, Pulmonary / immunology

Substances

  • Antibodies, Bacterial
  • Antigens, Bacterial
  • Bacterial Proteins
  • Glycolipids
  • Polysaccharides, Bacterial