Thyroid function and attention-deficit hyperactivity disorder

J Am Acad Child Adolesc Psychiatry. 1994 Feb;33(2):169-72. doi: 10.1097/00004583-199402000-00003.

Abstract

Objective: To examine thyroid indices in a community referred sample of boys with attention-deficit hyperactivity disorder (ADHD) for evidence of generalized resistance to thyroid hormone (GRTH).

Method: TSH, T3, and T4 values were gathered prospectively in 53 physician, school, and/or parent referred ADHD subjects, and in 41 age and gender-matched normal controls.

Results: None were in the range suggestive of global or pituitary thyroid hormone resistance.

Conclusions: GRTH is rare, and thyroid function should not be measured routinely in nonfamilial ADHD.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Attention Deficit Disorder with Hyperactivity / blood
  • Attention Deficit Disorder with Hyperactivity / diagnosis*
  • Attention Deficit Disorder with Hyperactivity / drug therapy
  • Attention Deficit Disorder with Hyperactivity / psychology
  • Child
  • Dextroamphetamine / therapeutic use
  • Double-Blind Method
  • Euthyroid Sick Syndromes / blood
  • Euthyroid Sick Syndromes / diagnosis*
  • Euthyroid Sick Syndromes / genetics
  • Euthyroid Sick Syndromes / psychology
  • Humans
  • Male
  • Methylphenidate / therapeutic use
  • Neurocognitive Disorders / blood
  • Neurocognitive Disorders / diagnosis*
  • Neurocognitive Disorders / drug therapy
  • Neurocognitive Disorders / psychology
  • Thyroid Function Tests*
  • Thyroid Hormones / blood

Substances

  • Thyroid Hormones
  • Methylphenidate
  • Dextroamphetamine