[Benign giant cell tumor of the tendon sheath. A differential diagnosis of cutaneous tumors near the joint]

Hautarzt. 1994 Jun;45(6):385-8. doi: 10.1007/s001050050088.
[Article in German]

Abstract

Giant cell tumour of the tendon sheath, though rather a common connective tissue tumour, is rarely mentioned in the dermatological literature. It is a benign, slow-growing tumour arising from the synovia and it is most frequently located on the joints of the fingers. It becomes manifest clinically as a firm, skin-coloured nodule fixed to the underlying tissue. The histological picture is characteristic and shows osteoclast-like giant cells, histiocytic cells, foam cells and focal haemosiderosis. It probably reflects a reactive process similar to that of fibrous histiocytoma. The therapy of choice is excision, with a small margin of uninvolved tissue to avoid recurrences.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Diagnosis, Differential
  • Elbow Joint / pathology
  • Female
  • Finger Joint / pathology
  • Giant Cells / pathology
  • Hemosiderosis / pathology
  • Humans
  • Male
  • Middle Aged
  • Skin / pathology
  • Skin Neoplasms / diagnosis*
  • Skin Neoplasms / pathology
  • Synovitis, Pigmented Villonodular / diagnosis*
  • Synovitis, Pigmented Villonodular / pathology