Stelazine-induced pigmentation

Clin Exp Dermatol. 1994 Mar;19(2):149-51. doi: 10.1111/j.1365-2230.1994.tb01145.x.

Abstract

A case of a West Indian patient is reported who developed abnormal blue-grey pigmentation on exposed areas of skin following treatment with low dose stelazine. Oculocutaneous melanosis is a well-recognized side-effect of prolonged phenothiazine treatment. In this condition the areas of skin exposed to sunlight develop a violaceous, blue-grey or slate-grey colour in more severe cases. These characteristic changes are rarely seen now. We describe the case of a patient who developed pigmentation while taking a low dose of stelazine for 5 years.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Humans
  • Pigmentation Disorders / chemically induced*
  • Pigmentation Disorders / pathology
  • Trifluoperazine / adverse effects*

Substances

  • Trifluoperazine