In modern production systems, the most economically limiting diseases are multifactorial enzootic health disorders. Relevant decisions in health management have to be based on rational procedures. A first-level approach implies the use of quantitative information on the economic impact of the disease. A more relevant approach of decisions regarding health problems consists of evaluating the economic worth of the interventions in terms of cost-effectiveness. Decision analysis and decision support are of interest today, particularly for herd health control schemes regarding enzootic disorders.