The authors performed a study in 14 top weightlifters, in order to make evident some effects of inosine. The athletes of A group received daily 1.5 g inosine (3 x 500 mg) for 6 weeks while the athletes of the B group (control group) received placebo. Six weeks inosine treatment induced significant changes for serum lipids and FFA (increase), urine mucoproteins (decrease), evoked muscular potential for the right median nerve and motric speed conductibility of the right external sciaticus popliteus nerve; the activity of serum CPK also increased. Some of these changes (CPK, evoked muscular potential, urine mucoproteins etc.) were evident even after 3 weeks of treatment.