Abstract
Two human genes containing NotI sites, ADP-ribosylation factor (ARF2) and melanoma NCK protein, were mapped by fluorescence in situ hybridization to 3p21.2-->p21.1 and 3q21, respectively. Thirteen other NotI-linking clones, representing sequence tagged sites, were also mapped to different regions of human chromosome 3. Two of these clones that contain sequences 80% homologous to the rat tropoelastin gene and brain Cl- channel protein CLC-2 gene probably represent new human genes closely related to the known rat genes.
Publication types
-
Comparative Study
-
Research Support, Non-U.S. Gov't
-
Research Support, U.S. Gov't, P.H.S.
MeSH terms
-
ADP-Ribosylation Factors
-
Adaptor Proteins, Signal Transducing
-
Animals
-
Carrier Proteins / genetics
-
Chromosome Mapping
-
Chromosomes, Human, Pair 3*
-
Deoxyribonucleases, Type II Site-Specific
-
GTP-Binding Proteins / genetics*
-
Genetic Linkage*
-
Hominidae / genetics*
-
Humans
-
In Situ Hybridization, Fluorescence / methods
-
Melanoma / genetics
-
Molecular Sequence Data
-
Oncogene Proteins / genetics*
-
Rats
-
Restriction Mapping*
Substances
-
Adaptor Proteins, Signal Transducing
-
Carrier Proteins
-
Nck protein
-
Oncogene Proteins
-
Deoxyribonucleases, Type II Site-Specific
-
GCGGCCGC-specific type II deoxyribonucleases
-
GTP-Binding Proteins
-
Arf2 protein, rat
-
ADP-Ribosylation Factors
-
ARF4 protein, human
Associated data
-
GENBANK/Z22238
-
GENBANK/Z22239
-
GENBANK/Z22240
-
GENBANK/Z22241
-
GENBANK/Z22242
-
GENBANK/Z22243
-
GENBANK/Z22244
-
GENBANK/Z22245
-
GENBANK/Z22246
-
GENBANK/Z22247
-
GENBANK/Z22248
-
GENBANK/Z22249
-
GENBANK/Z22250
-
GENBANK/Z22251
-
GENBANK/Z22252
-
GENBANK/Z22253
-
GENBANK/Z22254
-
GENBANK/Z22255
-
GENBANK/Z22256
-
GENBANK/Z22257
-
GENBANK/Z22258
-
GENBANK/Z22259
-
GENBANK/Z22260
-
GENBANK/Z22261
-
GENBANK/Z22262
-
GENBANK/Z22263
-
GENBANK/Z22264
-
GENBANK/Z22265
-
GENBANK/Z22266
-
GENBANK/Z22267