Experimental model of posterolateral spinal arthrodesis in sheep. Part 1. Experimental procedures and results with autologous bone graft

Spine (Phila Pa 1976). 1994 Dec 15;19(24):2791-7. doi: 10.1097/00007632-199412150-00011.

Abstract

Objectives: The authors evaluated the reliability in obtaining a posterolateral spinal arthrodesis (PSA) with autologous bone graft.

Summary of background data: Posterolateral spinal arthrodesis using autogenous cancellous bone graft is the most simple and efficient technique to get a spinal graft. No extensive biomechanical study of PSA is available. Thus, an experimental model of PSA is needed.

Methods: Eleven sheep underwent lumbar autologous bone grafts and Cotrel-Dubousset instrumentations, and four sheep were used as controls. Sacrifice and biomechanical evaluation of the lumbar spines were performed after 1 year.

Results: All grafts appeared continuous. A large decrease of flexibility (in rotation and in translation) was found in grafted spines in every direction. Failure in extension occurred at a mean value of 35.26 +/- 3.71 Nm.

Conclusion: A constant and homogenous PSA appears to be obtained in sheep under conditions close to the human surgery.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Biomechanical Phenomena
  • Bone Transplantation*
  • Sheep
  • Spinal Fractures / surgery
  • Spinal Fusion / methods*
  • Transplantation, Autologous