Epidermal growth factor receptors in Rous sarcoma virus-transformed cells of different hosts

Folia Biol (Praha). 1994;40(5):291-9.

Abstract

It was found that epidermal growth factor (EGF) binding on cells transformed by Rous sarcoma virus (RSV) differed in mice and hamsters. While EGF binding was considerably reduced in mouse tumours, the binding activity of hamster cells did not change after RSV transformation.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Avian Sarcoma Viruses / metabolism
  • Avian Sarcoma Viruses / physiology*
  • Blotting, Northern
  • Cell Transformation, Viral*
  • Cricetinae
  • ErbB Receptors / genetics
  • ErbB Receptors / metabolism*
  • Gene Expression / physiology
  • Humans
  • Iodine Radioisotopes
  • Mesocricetus
  • Mice
  • Receptors, Cell Surface
  • Tumor Cells, Cultured

Substances

  • Iodine Radioisotopes
  • Receptors, Cell Surface
  • ErbB Receptors