D1S80 allele frequencies in a Chinese population

N E Huang; R Chakraborty; B Budowle

doi:10.1007/BF01225597

D1S80 allele frequencies in a Chinese population

Int J Legal Med. 1994;107(3):118-20. doi: 10.1007/BF01225597.

Authors

N E Huang¹, R Chakraborty, B Budowle

Affiliation

¹ Criminal Investigation Bureau DNA Laboratory, Taipei, Taiwan, Republic of China.

PMID: 7893607
DOI: 10.1007/BF01225597

Abstract

Allele frequencies for the VNTR locus D1S80 were determined in a Chinese population sample using the polymerase chain reaction and subsequent analysis of the amplified products by polyacrylamide gel electrophoresis and silver staining. A total of 18 nominal D1S80 alleles were observed in 105 unrelated Chinese. The data demonstrate that D1S80 is highly polymorphic in Chinese with a heterozygosity of 90.5%. The D1S80 frequency distribution meets Hardy-Weinberg expectations. This D1S80 data can be used in forensic analyses and paternity tests to estimate the frequency of a DNA profile in a Chinese population.

MeSH terms

Alleles
Asian People / genetics*
Chromosome Mapping
DNA / analysis
Electrophoresis, Polyacrylamide Gel
Forensic Medicine / methods
Gene Frequency / genetics*
Genotype
Humans
In Vitro Techniques
Minisatellite Repeats*
Polymerase Chain Reaction

Substances

DNA