Abstract
12 population groups of Hungary, 1514 individuals altogether, have been studied for polymorphisms of alpha 1antitrypsin, serum cholinesterase, paraoxonase and delta-aminolevulinic acid dehydrase, N-acetyltransferase variation and aldehyde dehydrogenase deficiency. A possible relationship between their allele frequencies and environmental factors in the context of ecogenetic and pharmacogenetic phenomena in Hungary is discussed.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Adult
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Aldehyde Dehydrogenase / deficiency
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Aldehyde Dehydrogenase / genetics*
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Arylamine N-Acetyltransferase / deficiency
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Arylamine N-Acetyltransferase / genetics*
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Aryldialkylphosphatase
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Cholinesterases / blood
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Cholinesterases / deficiency
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Cholinesterases / genetics*
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Esterases / deficiency
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Esterases / genetics*
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Female
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Humans
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Hungary / ethnology
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Male
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Middle Aged
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Phenotype
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Polymorphism, Genetic*
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Porphobilinogen Synthase / deficiency
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Porphobilinogen Synthase / genetics*
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alpha 1-Antitrypsin / genetics*
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alpha 1-Antitrypsin Deficiency
Substances
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alpha 1-Antitrypsin
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Aldehyde Dehydrogenase
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Arylamine N-Acetyltransferase
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Esterases
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Cholinesterases
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Aryldialkylphosphatase
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Porphobilinogen Synthase