The birth of a neonate with congenital malformation for the parents determines often a process of adaptation with a phase of shock, a phase of incredibility and scare and, at last, one of adaptation and equilibration. The reactions of the parents and the difficulties they meet in the relation with the child depend mostly on the characteristics of the malformation and on the explanations and support they receive. The Health care personnel knows well that the communication of a diagnosis of a congenital malformation to the parents is frustrating. Both the Pediatrics and the Gynaecologist have to considerate seriously and consciously this relational question, considering that the communication is a interpersonal relationship and therefore flexible and changeable in every case. After this previous statement we consider it useful to report advises taken from the literature: the parents have to be informed at once the diagnosis is confirmed, possibly at the same time and in presence of the infant; the communication should be done both from the Pediatrics and the Gynaecologist, possibly at the same time; the communication should take place in a private atmosphere and with plenty of time.