Varacin and three new marine antimicrobial polysulfides from the far-eastern ascidian Polycitor sp

T N Makarieva; V A Stonik; A S Dmitrenok; B B Grebnev; V V Isakov; N M Rebachyk; Y W Rashkes

doi:10.1021/np50116a015

Varacin and three new marine antimicrobial polysulfides from the far-eastern ascidian Polycitor sp

J Nat Prod. 1995 Feb;58(2):254-8. doi: 10.1021/np50116a015.

Authors

T N Makarieva¹, V A Stonik, A S Dmitrenok, B B Grebnev, V V Isakov, N M Rebachyk, Y W Rashkes

Affiliation

¹ Laboratory of the Chemistry of Marine Natural Products, Pacific Institute of Bioorganic Chemistry, Russian Academy of Sciences.

PMID: 7769392
DOI: 10.1021/np50116a015

Abstract

Varacin [1] and three new antimicrobial marine polysulfides, varacins A-C [3-5], have been isolated from the Far Eastern ascidian Polycitor sp. Their structures have been elucidated by spectroscopic methods and by chemical transformations.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Anti-Bacterial Agents
Anti-Infective Agents / isolation & purification
Anti-Infective Agents / pharmacology*
Bacillus subtilis / drug effects
Candida albicans / drug effects
Chromatography, High Pressure Liquid
Ethylamines / isolation & purification
Ethylamines / pharmacology*
Magnetic Resonance Spectroscopy
Mass Spectrometry
Microbial Sensitivity Tests
Sulfides / isolation & purification
Sulfides / pharmacology*
Urochordata / chemistry*

Substances

Anti-Bacterial Agents
Anti-Infective Agents
Ethylamines
Sulfides
varacin A
varacin B
varacin C