We reviewed a complex nuclear medical method's application for investigating venous circulation of lower extremities--radionuclide venography (RVG) in explaining a case of suspective ileofemoral thrombosis. Suffering from pain and swelling of the right leg, patient T.J. wanted a checkup. After the physical examination, vascular surgeon suspected phlebothrombosis of the right ileofemoral region and immediately sent her to have a radionuclide venography (RVG) (because by Doppler-ultrasonography certain data confirming presence of thrombus in the pelvic region couldn't be gained). On the basis of gathered results vascular surgeon can make a final diagnosis (phlebothrombosis of the right vein femoralis), so that in this case flebography was not necessary. Although performing RVG is complex and requires engagement of experts of different profiles, gathered data are valuable because they cover the shortage of existing diagnostic methods which are most often used in routine work (Doppler-ultrasonography and phlebography). Applying RVG phlebography can be avoided in all patients who are not expected to have operative treatment, and in cases where thrombosis is suspected in deep veins of pelvis, RVG can be performed right away, without Doppler ultrasonography.