The growing concern about antisocial behavior and violence by children and adolescents has prompted several scientific reviews. Concurrently, 2 major scientific reviews of prevention have published reports. In addition, there has been an increase in the amount, complexity, and coordination of research on prediction and prevention of youth antisocial behavior. This special section is prompted by the co-occurrence of these developments, and it includes studies that focus on longitudinal prediction, testing of methods of risk screening, and evaluating interventions.