Flash P2 delay in primary degenerative dementia of the Alzheimer type

N C Moore; K A Tucker; M W Jann; R M Hostetler; K L Coburn

doi:10.1016/0278-5846(95)00021-m

Flash P2 delay in primary degenerative dementia of the Alzheimer type

Prog Neuropsychopharmacol Biol Psychiatry. 1995 May;19(3):403-10. doi: 10.1016/0278-5846(95)00021-m.

Authors

N C Moore¹, K A Tucker, M W Jann, R M Hostetler, K L Coburn

Affiliation

¹ Mercer University School of Medicine, Macon, Georgia, USA.

PMID: 7624491
DOI: 10.1016/0278-5846(95)00021-m

Abstract

1. Flash visual evoked responses of 31 patients meeting DSM-III-R criteria for primary degenerative dementia of the Alzheimer type were compared with 31 healthy controls. 2. P1 latency was normal (75 +/- 6 msec Alzheimer's; 75 +/- 6 msec controls). 3. P2 was significantly delayed (162 +/- 32 msec, 147 +/- 20 msec, p < 0.03) among patients. 4. P1-P2 interpeak latency was significantly increased (87 +/- 32 msec, 71 +/- 21 msec, p < 0.03) among patients.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aged
Alzheimer Disease / diagnosis*
Alzheimer Disease / physiopathology
Brain Mapping
Electroencephalography
Evoked Potentials, Visual / physiology*
Humans
Photic Stimulation
Visual Cortex / physiopathology