Transverse nail ridgings (Beau's lines) induced by chemotherapy

Acta Haematol. 1994;91(2):89-90. doi: 10.1159/000204261.

Abstract

Transverse grooves of the nails, designated as Beau's lines, were observed in a patient with malignant lymphoma given chemotherapy. Beau's lines disappeared in the treatment-free intervals. This observation supports the concept that these lines are the result of the suppressed growth of the nail matrix caused by antimitotic drugs.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Antineoplastic Combined Chemotherapy Protocols / adverse effects*
  • Bleomycin / adverse effects
  • Cisplatin / adverse effects
  • Cyclophosphamide / adverse effects
  • Dexamethasone / adverse effects
  • Doxorubicin / adverse effects
  • Etoposide / adverse effects
  • Head and Neck Neoplasms / complications
  • Head and Neck Neoplasms / drug therapy
  • Humans
  • Ifosfamide / adverse effects
  • Lymphoma, Non-Hodgkin / complications
  • Lymphoma, Non-Hodgkin / drug therapy
  • Male
  • Nail Diseases / chemically induced*
  • Nail Diseases / pathology
  • Nails / drug effects
  • Nails / pathology
  • Prednisone / adverse effects
  • Vincristine / adverse effects

Substances

  • Bleomycin
  • Vincristine
  • Etoposide
  • Dexamethasone
  • Doxorubicin
  • Cyclophosphamide
  • Cisplatin
  • Ifosfamide
  • Prednisone

Supplementary concepts

  • DICE protocol
  • VACOP-B protocol