Treatment of upper airways inflammation with nimesulide

Drugs. 1993:46 Suppl 1:107-10. doi: 10.2165/00003495-199300461-00022.

Abstract

Nimesulide treatment for 7 to 10 days is shown to be effective in controlling the inflammatory process in upper airways disorders such as rhinitis, rhinosinusitis, rhinopharyngitis and tubaritis, and in middle ear disorder (secretory otitis media). A concomitant antibacterial is considered necessary in cases involving infection, in order to retain the improvements in mucociliary transport obtained with anti-inflammatory treatment. Nimesulide is also shown to be effective when given in combination with the mucolytic drug ambroxol.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Ambroxol / administration & dosage
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use*
  • Child
  • Drug Therapy, Combination
  • Humans
  • Middle Aged
  • Otitis Media with Effusion / drug therapy*
  • Pharyngitis / drug therapy*
  • Rhinitis / drug therapy*
  • Single-Blind Method
  • Sulfonamides / administration & dosage
  • Sulfonamides / therapeutic use*
  • Tonsillitis / drug therapy*

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Sulfonamides
  • Ambroxol
  • nimesulide