Abstract
Nimesulide treatment for 7 to 10 days is shown to be effective in controlling the inflammatory process in upper airways disorders such as rhinitis, rhinosinusitis, rhinopharyngitis and tubaritis, and in middle ear disorder (secretory otitis media). A concomitant antibacterial is considered necessary in cases involving infection, in order to retain the improvements in mucociliary transport obtained with anti-inflammatory treatment. Nimesulide is also shown to be effective when given in combination with the mucolytic drug ambroxol.
Publication types
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Clinical Trial
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Randomized Controlled Trial
MeSH terms
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Adolescent
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Adult
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Aged
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Ambroxol / administration & dosage
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Anti-Inflammatory Agents, Non-Steroidal / therapeutic use*
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Child
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Drug Therapy, Combination
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Humans
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Middle Aged
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Otitis Media with Effusion / drug therapy*
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Pharyngitis / drug therapy*
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Rhinitis / drug therapy*
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Single-Blind Method
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Sulfonamides / administration & dosage
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Sulfonamides / therapeutic use*
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Tonsillitis / drug therapy*
Substances
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Anti-Inflammatory Agents, Non-Steroidal
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Sulfonamides
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Ambroxol
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nimesulide