Using the clinico-catamnestic method (supplemented with some laboratory examinations) the author observed 126 patients with neuroses, in the clinical picture of which systemic disorders were prevalent. It was found that among patients with the neuroses accompanied with vegetative dystonia and cardiac disturbances those suffering from neurasthenia were predominant, while among patients with neurotic respiratory and gastrointestinal disturbances most were suffering from hysteria. In the latter patients a great variability of the neurotic syndromes was noted. Pathogenetic psychotherapy of that pathology appeared to be sufficiently effective: 75.4% of the patients recovered or showed a stable improvement. Any direct participation of the neurotic somatic disorders in development of organic impairments in the respective somatic systems was not revealed.